AL-100: Benchtop Air Lift BioReactor
AL-100: Benchtop Air Lift BioReactor
Industrial grade PLC control system
8” HMI touch panel
Equipped with thermally controlled jacketed vessel
Software-based calibration
Communication protocol: two way RS485 and Ethernet interface for remote monitoring and control anywhere and anytime.
Simple and flexible parameter settings
Custom-dimension construction available
Autoclave sterilization or optional semi-automated SIP (see below)
[OPTIONAL] Semi-automated Steam Sterilization in Place (SIP) using a stainless steel (S/S) cylindrical cover sealed to the S/S jacketed base. Sterilization temperature is controlled with the steam inlet generated from a steam generator such as a small lab autoclave. In general, most lab autoclaves can accommodate 5L bioreactor vessels with heights less than 70 cm.
Design Features
Specifications
Headplate/Vessel
PID control
Built-in pressure regulator
Multi-functional advanced D.O. control
Programmable peristaltic pumps for volume measurement
Open frame for easy operation and maintenance
Battery-protected memory stores vital parameters
pH/DO auto-calibration by software
RS485 digital output of all measurements
Remote control capability through Ethernet.
Vessel total volume: 5, 10 Liters
Temperature control range: 5 degC above ambient to 60 deg C
Mixer speed: 0 to 1000 rpm (if optional agitator requested)
Air inflow volume: 0.5-10 slpm (5L)*
*Air flow rate is manually controlled by a rotameter and is used to maintain constant liquid circulation rate within the vessel.
pH control range: 2.00-12.00
DO control range: maintain DO above the setpoint, controlled by cascade AIR-in or oxygen pressure**
**It is most efficient to use O2 and head pressure to control DO. To control O2, an additional rotameter with a ON/OFF control valve [OPTIONAL] is required.
To control head pressure of the vessel, a pressure control module is required [OPTIONAL].
A mass flow controller (MFC) is not required unless customer needs to continually control and monitor air flow rate.
Air filter for inlet and exhaust: 0.2 μm (autoclavable)
Type of foaming probe: conductivity
Communication protocol: two way RS485 and Ethernet interface for remote monitoring, control, and interface between user's computer and control console for data logging & remote operation
Peristaltic pumps: programmable for acid addition, base addition, defoaming, and/or feeding
Device dimensions:
(5L) 10.2cmW x 62cmH
(10L) 13.4cmW x 75cmH (approx.)
Standard dimensions — systems can be constructed to customer's specifications.
Equipment weight: 70 KG (approx.)
Bottom Stainless steel / thermal jacketed
Upper reinforced glass vessel
Sampling tube from top into bottom (6 or 8mm)
Roof mounted pH / DO port (12mm)
Three (3) standard 12 mm feeding
Height-adjustable foaming probe
Temperature probe port (8mm)
Equipped with air condenser
[OPTIONAL] Top plate mounted AC-servo motor driven control mixer*
*At small scale, some customers may require additional agitation if their process application involves high solid contents, large cell aggregate, or for foam breaking purposes.
[OPTIONAL] Mass air-flow meter
[OPTIONAL] Turbidity measurement for optical density